Purification and characterisation of the antifungal
and antibacterial compounds produced by the yeast Torulaspora delbruckii, associated
with the clam Venerupis decussata
H. Aassila1*, M. Guyot2, S. Rifai1, A. Fassouane1
1 Laboratoire de Biochimie, Faculté des Sciences, Université Chouaib Doukkali, BP 20, 24000 El Jadida, Maroc.
2Unité MCAM, UMR 7245 CNRS/MNHN, Dept. RDDM. Case postale 54 (63 rue Buffon) ?57 rue Cuvier, 75005 Paris France
* Corresponding authors. E-mail address : firstname.lastname@example.org
Received: 25 July 2012; revised version accepted: 12 March 2013
Succinic acid and deoxycholic acid were identified as antibiotic substances produced by the clam-associated yeast Torulaspora delbruckii. Our study is the first report of the antifungal and antibacterial activities of 1,4- butanedioic acid, toward pathogenic and ichtyopathogenic strains. We have also shown the antibacterial activity of deoxycholic acid against Staphylococcus aureus.
Keywords: Antifungal activity; Antibacterial activity; Torulaspora delbruckii; Venerupis decussata; Succinic acid; Deoxycholic acid.