Purification and characterisation of the antifungal

and antibacterial compounds produced by the yeast Torulaspora delbruckii, associated

with the clam Venerupis decussata


H. Aassila1*, M. Guyot2, S. Rifai1, A. Fassouane1

1 Laboratoire de Biochimie, Faculté des Sciences, Université Chouaib Doukkali, BP 20,  24000 El Jadida, Maroc.

2Unité MCAM, UMR 7245 CNRS/MNHN, Dept. RDDM. Case postale 54 (63 rue Buffon) ?57 rue Cuvier, 75005 Paris France

* Corresponding authors.  E-mail address : aahinde@hotmail.fr

Received: 25 July 2012; revised version accepted: 12 March 2013



     Succinic acid and deoxycholic acid were identified as antibiotic substances produced by the clam-associated yeast Torulaspora delbruckii. Our study is the first report of the antifungal and antibacterial activities of 1,4- butanedioic acid, toward pathogenic and ichtyopathogenic strains. We have also shown the antibacterial activity of deoxycholic acid against Staphylococcus aureus.


Keywords: Antifungal activity; Antibacterial activity; Torulaspora delbruckii; Venerupis decussata; Succinic acid; Deoxycholic acid.


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