Condensation of allylmagnesium chloride on R-(-)-Carvone

L. Majidi1*, R. Fihi1, M. El Idrissi2, S. Kharchouf1

1Laboratoire des substances naturelles & synthèse et dynamique moléculaire, UFR Valorisation des Substances Naturelles et Environnement, Faculté des Sciences et Techniques,

Département de Chimie, Errachidia, Morocco

2Laboratoire de chimie organique appliquée, Faculté des Sciences, Département de Chimie, Meknès, Morocco

* Corresponding author. E-mail: lmajidi@yahoo.fr

Received : 16 February 2005; revised version accepted :09 May 2005

Abstract

The addition of allylic Grignard reagents to R-(-)-carvone and 2-(2-methylpropylidene) cyclohexanone is regio and stereoselective. The stereochemistry assignment of allylcarveols 5-7 and allyl-2-(2-methylpropylidene) cyclohexanols 17-19 is based on infrared and NMR spectral studies.

Keywords : Carvone; Allylcarveols; Organomagnesium; Regioselectivity; Stereoselectivity.

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