Natural phosphate efficient and selective catalyst

for the oxidative cleavage

of cyclic ketones to ketoacids using dioxygen

 

M. Dakkach1, Y. Mahha1, A. Atlamsani1*, S. Sebti2

1 Université Abdelmalek Essaâdi, Faculté des Sciences, Laboratoire de Physico-Chimie des Interfaces et Environnement,

B.P. 2121, 93000 Tétouan, Maroc

2 Université Hassan II - Mohammedia, Faculté des Sciences Ben M’Sik,

Laboratoire de Chimie Organique, Catalyse et Environnement, B.P. 7955, 20702 Casablanca, Maroc

* Corresponding author. E-mail: atlamsani@fst.ac.ma

Received: 26 June 2008; revised version accepted: 04 November 2008

 

Abstract

     Natural phosphate (NP) is used as heterogeneous catalyst in direct dioxygen oxidation of cycloalkanones to give ketoacids. Treatment of these substrates with a catalytic amount of NP under O2 atmosphere gives products in good yields. The selectivity observed at high conversions with various ketones, coupled with mild conditions and inexpensive oxidant, would seem to make this method attractive for use in fine chemical manufacture. The effects of solvent, reaction times, weight of catalyst on oxidation are considered. This reaction might also represent an alternative to the process carried out in homogeneous media, which is characterized by a no longer acceptable environmental impact.

 

Keywords: Natural phosphate; Dioxygen; Oxidative C-C bond cleavage.

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